SP-0396: Can we perform RCTs evaluating MR guided radiotherapy?

Can we perform spinal 1H-MR spectroscopy in daily clinical practice?

Mr Mom: can we deliver?

Man’s age-old fascination with the idea of male pregnancy is evident from numerous references to it in ancient mythology. Today, in the wake of the in vitro fertilisation (IVF) revolution and other examples of innovative reproductive technology opening up a world of reproductive possibility, the thought of procreation sans female captivates the public consciousness more than ever. Several attem...

Evaluating Ebola therapies--the case for RCTs.

T worst Ebola epidemic in history is ongoing. With the number of deaths from Ebola virus disease (EVD) already in the thousands and predicted to rise to tens of thousands,1 the situation is tragic. No treatments have yet been shown to be safe and effective in patients with EVD. Some candidate therapies have shown benefit in animal models of infection, and others have shown activity against cert...

MR-guidance – a clinical study to evaluate a shuttle- based MR-linac connection to provide MR-guided radiotherapy

BACKGROUND The purpose of this clinical study is to investigate the clinical feasibility and safety of a shuttle-based MR-linac connection to provide MR-guided radiotherapy. METHODS/DESIGN A total of 40 patients with an indication for a neoadjuvant, adjuvant or definitive radiation treatment will be recruited including tumors of the head and neck region, thorax, upper gastrointestinal tract a...

Evaluating payment mechanisms: how can we measure unnecessary care?

There has been substantial concern that linking hospital or physician remuneration to the amount of care provided will encourage excessive provision of health care. Studies that seek to explore this relationship require methods to measure unnecessary care. This paper presents and discusses a method used to assess the magnitude of unnecessary care in the context of an evaluation of the impact of...